{"id":791126,"date":"2022-06-02T14:01:03","date_gmt":"2022-06-02T12:01:03","guid":{"rendered":"https:\/\/bebeez.it\/non-categorizzato\/endpoint-health-raises-52-million-in-financing-to-expand-and-progress-precision-immunology-pipeline\/"},"modified":"2023-07-11T10:48:33","modified_gmt":"2023-07-11T08:48:33","slug":"endpoint-health-raises-52-million-in-financing-to-expand-and-progress-precision-immunology-pipeline","status":"publish","type":"post","link":"https:\/\/bebeez.it\/en\/private-capital-in-north-america\/endpoint-health-raises-52-million-in-financing-to-expand-and-progress-precision-immunology-pipeline\/","title":{"rendered":"Endpoint Health Raises $52 Million in Financing to Expand and Progress Precision Immunology Pipeline"},"content":{"rendered":"

\nThe company plans to submit its first Investigational New Drug (IND) application later this year\n<\/p>\n

PALO ALTO, Calif.–(BUSINESS WIRE)–Endpoint Health, Inc., a Precision-FirstTM therapeutics company dedicated to addressing unmet needs in immune-mediated acute and chronic diseases, today announced the close of $52 million in equity and debt financing. Major institutional investors participating in the Series A round included Mayfield, Humboldt Fund, AME Cloud Ventures, Boom Capital, Alix Ventures, Yaya Capital, Wireframe Ventures, The Venture Collective, HCX Ventures and Global Health Investment Corporation (GHIC).\n<\/p>\n

<\/a><\/p>\n

\nProceeds from the financing round will be used to extend the company\u2019s Precision-FirstTM platform and expand its therapeutic pipeline to include programs for chronic immune-mediated diseases. In addition, proceeds will be used to advance Antithrombin III, the company\u2019s first precision therapy, to a Phase II clinical trial for the treatment of sepsis. The company expects to submit its Investigational New Drug (IND) application and Investigational Device Exemption (IDE) to the US Food and Drug Administration (FDA) for its Antithrombin III program later this year.\n<\/p>\n

\n\u201cAt Endpoint Health, we\u2019re building a new kind of biopharma company that\u2019s uniquely designed for a new era of precision medicine. This funding provides us with additional resources to accelerate our mission to deliver precision therapies to patients with acute and chronic immune-mediated inflammatory diseases,\u201d said Jason Springs, co-founder and Chief Executive Officer. \u201cWe combine AI, therapeutics and therapy-guiding tests to rewrite the molecule-first drug development model. We are creating a new approach with the goal of bringing the promise of precision therapeutics to immunology.\u201d\n<\/p>\n

\nThere is an urgent need for new therapies to treat immune-mediated chronic and acute diseases, which affect approximately 5%-7% and 14% of the world\u2019s population, respectively.1, 2 For example, sepsis is responsible for one in every five deaths worldwide1, yet there are few FDA-approved therapies to treat the condition. Additionally, while there are approximately 500 million people with chronic immune-mediated diseases, in some of the most common conditions, such as inflammatory bowel disease (IBD), nearly half of patients fail to achieve an adequate clinical response to currently available therapies.3<\/p>\n

\n\u201cEndpoint Health\u2019s precision approach to deeply understand the immune state of patients and use that knowledge to develop precision therapies is exactly the type of innovation we search for,\u201d said Charlie Petty, partner at GHIC, which recently announced a venture capital partnership with the Biomedical Advanced Research and Development Authority (BARDA) to accelerate the development and commercialization of technologies to address global public health emergencies. \u201cOur mission, supported by our unique relationship with BARDA and other strategic partners, is to support life sciences companies with the vision to transform health security. With its proprietary AI platform and an experienced leadership team with a track record of success in both diagnostics and therapeutics, Endpoint Health is well-positioned to develop new precision therapies for patients in need.\u201d\n<\/p>\n

\nCompletion of the Series A financing follows Endpoint Health\u2019s recent announcement<\/a> of a global collaboration and licensing agreement with Grifols to develop and commercialize Antithrombin III in sepsis.\n<\/p>\n

\nAbout Endpoint Health\n<\/p>\n

\nEndpoint Health is a Precision-FirstTM therapeutics company dedicated to addressing unmet needs in immune-mediated acute and chronic diseases. We combine therapeutics, therapy-guiding tests, and AI to develop precision therapies for patients with immune-mediated conditions, such as acute respiratory distress syndrome (ARDS), sepsis, rheumatic and gastroenterologic diseases. Our vision is a world in which all patients get the best treatment possible for their unique biology and disease. For more information, visit www.endpointhealth.com<\/a>.\n<\/p>\n

\nFollow us on Social Media: LinkedIn<\/a>, Twitter<\/a>\n<\/p>\n

\nReferences\n<\/p>\n

World Health Organization, Accessed at https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/sepsis<\/a><\/p>\n

El-Gabalawy H, Guenther Lyn, et al. Epidemiology of immune-mediated inflammatory diseases: incidence, prevalence, natural history, and comorbidities. Rheumatol Suppl. 2010 May;85:2-10. doi: 10.3899\/jrheum.091461<\/p>\n

Chang JT. Pathophysiology of Inflammatory Bowel Diseases. N Engl J Med. 2020 Dec 31;383(27):2652-2664. doi: 10.1056\/NEJMra2002697<\/p>\n

Contacts <\/p>\n

\nChristian Pflaumer
\n
Ruder Finn
\n
917.841.4525
\n
Christian.Pflaumer@ruderfinn.com<\/a><\/p>","protected":false},"excerpt":{"rendered":"

The company plans to submit its first Investigational New Drug (IND) application later this year PALO ALTO, Calif.–(BUSINESS WIRE)–Endpoint Health, Inc., a Precision-FirstTM therapeutics company dedicated to addressing unmet needs in immune-mediated acute and chronic diseases, today announced the close of $52 million in equity and debt financing. Major institutional investors participating in the Series […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[49625],"tags":[],"settori":[],"slider_categorie_and_home_page":[],"class_list":["post-791126","post","type-post","status-publish","format-standard","hentry","category-private-capital-in-north-america"],"acf":[],"yoast_head":"\nEndpoint Health Raises $52 Million in Financing to Expand and Progress Precision Immunology Pipeline - BeBeez<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/bebeez.it\/en\/private-capital-in-north-america\/endpoint-health-raises-52-million-in-financing-to-expand-and-progress-precision-immunology-pipeline\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Endpoint Health Raises $52 Million in Financing to Expand and Progress Precision Immunology Pipeline - BeBeez\" \/>\n<meta property=\"og:description\" content=\"The company plans to submit its first Investigational New Drug (IND) application later this year PALO ALTO, Calif.–(BUSINESS WIRE)–Endpoint Health, Inc., a Precision-FirstTM therapeutics company dedicated to addressing unmet needs in immune-mediated acute and chronic diseases, today announced the close of $52 million in equity and debt financing. 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